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This work was supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan; by a Research Grant from the Human Frontier Science Program K.F. and E.M. and by the Grant from the Ministry of Health and Welfare K.M. ; . 2 Correspondence: Eishichi Miyamoto, Department of Pharmacology, Kumamoto University School of Medicine, 221 Honjo, Kumamoto 8600811, Japan. FAX: 81 96 3735078; e-mail: emiyamot gpo.kumamoto-u.ac.jp.

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Chloromycetin aplicaps The concentration-dependent nature of these effects is the basis for the clinical importance of the pharmacokinetic differences among ssris table 2. PRESCRIBING INFORMATION .1 TABLE OF CONTENTS .2 PART I: HEALTH PROFESSIONAL INFORMATION .3 SUMMARY PRODUCT INFORMATION.3 INDICATIONS AND CLINICAL USE .3 CONTRAINDICATIONS.3 WARNINGS AND PRECAUTIONS .3 ADVERSE REACTIONS .7 DRUG INTERACTIONS .7 DOSAGE AND ADMINISTRATION .9 OVERDOSAGE.11 ACTION AND CLINICAL PHARMACOLOGY.12 STORAGE AND STABILITY .13 DOSAGE FORMS, COMPOSITION AND PACKAGING.14 PART III: CONSUMER INFORMATION.15. DIVISION OF AIDS HIV Prevention Trials Network HPTN ; INFORMED CONSENT FORM SPECIMEN STORAGE HPTN 056: Characterization of baseline mucosal indices of injury and inflammation in men for use in rectal microbicide trials Final Version 1.0 02 December 2003 INTRODUCTION You have decided to take part in a National Institute of Health NIH ; Division of AIDS research study. While you are in this research study there may be some samples blood, fluid, and tissue ; taken from you that might be useful for future research. You are being asked to agree to the storage of these samples. This consent form gives you information about the collection, storage and use of your samples. The study staff will talk with you about this information. Please ask if you have any questions. If you agree to the storage of your samples, you will be asked to sign this consent form. You will get a copy to keep. You may decide not to have any samples stored other than what is needed to complete this study and still be in this research study or any future study. On the checklist at the end of this consent form, you will be asked to indicate if you would permit part of these samples to be shared with other researchers. If you agree to have your sample shared with other researchers and later decide to withdraw, we may not be able to retrieve any or all of your samples from other researchers. The researcher is not required to store your sample s ; indefinitely. HOW WILL YOU GET THE SAMPLES FROM ME? There will be NO ADDITIONAL samples taken from you for storage. After all the tests are done for this research study, there may be some left over samples of blood, fluid, and tissue. If you agree, left over samples will be kept and used for future research. HOW WILL YOU USE MY SAMPLES? Your samples will only be used to look for immune or viral responses that may play an important role in understanding HIV AIDS infection. Tests may also include examining your genes DNA ; , since they might affect your response to disease in important ways. Your genes might make you more or less susceptible to becoming infected, your responses to infection or to treatment stronger or weaker, or make HIV progress more rapidly or slowly. No other kinds of genetic test will be done by anyone on your stored specimens without first explaining the test to you and obtaining your permission.

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